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Naltrexone Facilitates Learning and Delays Extinction by Increasing AMPA Receptor Phosphorylation and Membrane Insertion

BACKGROUND: The opioid antagonists, naloxone/naltrexone, are involved in improving learning and memory, but their cellular and molecular mechanisms remain unknown. We investigated the effect of naloxone/naltrexone on hippocampal AMPAR trafficking, a molecular substrate of learning and memory, as a p...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biol Psychiatry
Main Authors: Kibaly, Cherkaouia, Kam, Angel Y.F., Loh, Horace H., Law, Ping-Yee
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4630208/
https://ncbi.nlm.nih.gov/pubmed/26049209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2015.04.019
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