Src‐dependent phosphorylation of μ‐opioid receptor at Tyr(336) modulates opiate withdrawal

Opiate withdrawal/negative reinforcement has been implicated as one of the mechanisms for the progression from impulsive to compulsive drug use. Increase in the intracellular cAMP level and protein kinase A (PKA) activities within the neurocircuitry of addiction has been a leading hypothesis for opi...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Zhang, Lei, Kibaly, Cherkaouia, Wang, Yu‐Jun, Xu, Chi, Song, Kyu Young, McGarrah, Patrick W, Loh, Horace H, Liu, Jing‐Gen, Law, Ping‐Yee
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666313/
https://ncbi.nlm.nih.gov/pubmed/28818835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201607324
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