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Morphine Induces AMPA Receptor Internalization in Primary Hippocampal Neurons via Calcineurin-Dependent Dephosphorylation of GluR1 Subunits
Chronic morphine treatment resulting in the alteration of postsynaptic levels of AMPA receptors, thereby modulating synaptic strength, has been reported. However, the mechanism underlying such drug-induced synaptic modification has not been resolved. By monitoring the GluR1 trafficking in primary hi...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Society for Neuroscience
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3073525/ https://ncbi.nlm.nih.gov/pubmed/21068335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4255-10.2010 |
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