Mesenchymal Deficiency of Notch1 Attenuates Bleomycin-Induced Pulmonary Fibrosis

Notch signaling pathway is involved in the regulation of cell fate, differentiation, proliferation, and apoptosis in development and disease. Previous studies suggest the importance of Notch1 in myofibroblast differentiation in lung alveogenesis and fibrosis. However, direct in vivo evidence of Notc...

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Detalles Bibliográficos
Publicado en:Am J Pathol
Autores principales: Hu, Biao, Wu, Zhe, Bai, David, Liu, Tianju, Ullenbruch, Matthew R., Phan, Sem H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2015
Materias:
Regular Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4630167/
https://ncbi.nlm.nih.gov/pubmed/26358219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.07.014
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