Farnesylated and methylated KRAS4b: high yield production of protein suitable for biophysical studies of prenylated protein-lipid interactions

Prenylated proteins play key roles in several human diseases including cancer, atherosclerosis and Alzheimer’s disease. KRAS4b, which is frequently mutated in pancreatic, colon and lung cancers, is processed by farnesylation, proteolytic cleavage and carboxymethylation at the C-terminus. Plasma memb...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Sci Rep
المؤلفون الرئيسيون: Gillette, William K., Esposito, Dominic, Abreu Blanco, Maria, Alexander, Patrick, Bindu, Lakshman, Bittner, Cammi, Chertov, Oleg, Frank, Peter H., Grose, Carissa, Jones, Jane E., Meng, Zhaojing, Perkins, Shelley, Van, Que, Ghirlando, Rodolfo, Fivash, Matthew, Nissley, Dwight V., McCormick, Frank, Holderfield, Matthew, Stephen, Andrew G.
التنسيق: Artigo
اللغة:Inglês
منشور في: Nature Publishing Group 2015
الموضوعات:
Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629113/
https://ncbi.nlm.nih.gov/pubmed/26522388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15916
الوسوم: إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

مواد مشابهة