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A genetic variant of cortactin linked to acute lung injury impairs lamellipodia dynamics and endothelial wound healing
Inflammatory mediators released in acute lung injury (ALI) trigger the disruption of interendothelial junctions, leading to loss of vascular barrier function, protein-rich pulmonary edema, and severe hypoxemia. Genetic signatures that predict patient recovery or disease progression are poorly define...
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| Yayımlandı: | Am J Physiol Lung Cell Mol Physiol |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Physiological Society
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4628987/ https://ncbi.nlm.nih.gov/pubmed/26361873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00062.2015 |
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