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A genetic variant of cortactin linked to acute lung injury impairs lamellipodia dynamics and endothelial wound healing
Inflammatory mediators released in acute lung injury (ALI) trigger the disruption of interendothelial junctions, leading to loss of vascular barrier function, protein-rich pulmonary edema, and severe hypoxemia. Genetic signatures that predict patient recovery or disease progression are poorly define...
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| Publicado no: | Am J Physiol Lung Cell Mol Physiol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4628987/ https://ncbi.nlm.nih.gov/pubmed/26361873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00062.2015 |
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