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Homocysteine Impairs Endothelial Wound Healing by Activating Metabotropic Glutamate Receptor 5

OBJECTIVE: Hcy is an independent risk factor for cerebrovascular disease and cognitive impairment. The purpose of this study was to elucidate the role of mGluR5 in Hcy-mediated impairment of cerebral endothelial wound repair. METHODS: Mouse CMVECs (bEnd.3) were used in conjunction with directed phar...

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Detalhes bibliográficos
Publicado no:Microcirculation
Main Authors: CHEN, CHENG-HUNG, BEARD, RICHARD S., BEARDEN, SHAWN E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359906/
https://ncbi.nlm.nih.gov/pubmed/22221504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1549-8719.2012.00159.x
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