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Metabotropic Glutamate Receptor 5 Mediates Phosphorylation Of Vascular Endothelial Cadherin And Nuclear Localization Of β-catenin In Response to Homocysteine
Elevated plasma homocysteine (Hcy) is an independent risk factor for vascular disease and stroke in part by causing generalized endothelial dysfunction. A receptor that is sensitive to Hcy and its intracellular signaling systems has not been identified. β-catenin is a pleiotropic regulator of transc...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3304005/ https://ncbi.nlm.nih.gov/pubmed/22285407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vph.2012.01.004 |
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