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Ligand independent mechanisms of Notch activity
Interaction between the Notch receptor and Delta-Serrate-Lag2 (DSL) ligands is generally deemed to be the starting point of the Notch signaling cascade, after which, Notch is cleaved and the intracellular domain acts as a transcriptional co-activator. By contrast, Notch protein can become activated...
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| Pubblicato in: | Trends Cell Biol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4628868/ https://ncbi.nlm.nih.gov/pubmed/26437585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2015.07.010 |
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