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Targeting Protein Aggregation for the Treatment of Degenerative Diseases

The aggregation of specific proteins is hypothesized to underlie several degenerative diseases, collectively called amyloid disorders. However, the mechanistic connection between the process of protein aggregation and tissue degeneration is not yet fully understood. Here, we review current and emerg...

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Detalles Bibliográficos
Publicado en:Nat Rev Drug Discov
Main Authors: Eisele, Yvonne S., Monteiro, Cecilia, Fearns, Colleen, Encalada, Sandra E., Wiseman, R. Luke, Powers, Evan T., Kelly, Jeffery W.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628595/
https://ncbi.nlm.nih.gov/pubmed/26338154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd4593
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