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Targeting Protein Aggregation for the Treatment of Degenerative Diseases

The aggregation of specific proteins is hypothesized to underlie several degenerative diseases, collectively called amyloid disorders. However, the mechanistic connection between the process of protein aggregation and tissue degeneration is not yet fully understood. Here, we review current and emerg...

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Pubblicato in:Nat Rev Drug Discov
Autori principali: Eisele, Yvonne S., Monteiro, Cecilia, Fearns, Colleen, Encalada, Sandra E., Wiseman, R. Luke, Powers, Evan T., Kelly, Jeffery W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628595/
https://ncbi.nlm.nih.gov/pubmed/26338154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd4593
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