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Targeting Protein Aggregation for the Treatment of Degenerative Diseases

The aggregation of specific proteins is hypothesized to underlie several degenerative diseases, collectively called amyloid disorders. However, the mechanistic connection between the process of protein aggregation and tissue degeneration is not yet fully understood. Here, we review current and emerg...

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Publicat a:Nat Rev Drug Discov
Autors principals: Eisele, Yvonne S., Monteiro, Cecilia, Fearns, Colleen, Encalada, Sandra E., Wiseman, R. Luke, Powers, Evan T., Kelly, Jeffery W.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628595/
https://ncbi.nlm.nih.gov/pubmed/26338154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd4593
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