Marine alkaloid Monanchocidin a overcomes drug resistance by induction of autophagy and lysosomal membrane permeabilization

Monanchocidin A (MonA) is a novel alkaloid recently isolated from the marine sponge Monanchora pulchra. The compound reveals cytotoxic activity in genitourinary cancers including cisplatin-sensitive and -resistant germ cell tumor (GCT) cell lines, hormone-sensitive and castration-resistant prostate...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Dyshlovoy, Sergey A., Hauschild, Jessica, Amann, Kerstin, Tabakmakher, Ksenia M., Venz, Simone, Walther, Reinhard, Guzii, Alla G., Makarieva, Tatiana N., Shubina, Larisa K., Fedorov, Sergey N., Stonik, Valentin A., Bokemeyer, Carsten, Balabanov, Stefan, Honecker, Friedemann, Amsberg, Gunhild v.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627311/
https://ncbi.nlm.nih.gov/pubmed/26093146
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