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Inactivated Influenza Vaccine That Provides Rapid, Innate-Immune-System-Mediated Protection and Subsequent Long-Term Adaptive Immunity

The continual threat to global health posed by influenza has led to increased efforts to improve the effectiveness of influenza vaccines for use in epidemics and pandemics. We show in this study that formulation of a low dose of inactivated detergent-split influenza vaccine with a Toll-like receptor...

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Bibliografiske detaljer
Udgivet i:mBio
Main Authors: Chua, Brendon Y., Wong, Chinn Yi, Mifsud, Edin J., Edenborough, Kathryn M., Sekiya, Toshiki, Tan, Amabel C. L., Mercuri, Francesca, Rockman, Steve, Chen, Weisan, Turner, Stephen J., Doherty, Peter C., Kelso, Anne, Brown, Lorena E., Jackson, David C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626850/
https://ncbi.nlm.nih.gov/pubmed/26507227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01024-15
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