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Inactivated Influenza Vaccine That Provides Rapid, Innate-Immune-System-Mediated Protection and Subsequent Long-Term Adaptive Immunity

The continual threat to global health posed by influenza has led to increased efforts to improve the effectiveness of influenza vaccines for use in epidemics and pandemics. We show in this study that formulation of a low dose of inactivated detergent-split influenza vaccine with a Toll-like receptor...

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Detalles Bibliográficos
Publicado en:mBio
Main Authors: Chua, Brendon Y., Wong, Chinn Yi, Mifsud, Edin J., Edenborough, Kathryn M., Sekiya, Toshiki, Tan, Amabel C. L., Mercuri, Francesca, Rockman, Steve, Chen, Weisan, Turner, Stephen J., Doherty, Peter C., Kelso, Anne, Brown, Lorena E., Jackson, David C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Microbiology 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626850/
https://ncbi.nlm.nih.gov/pubmed/26507227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01024-15
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