Hepatitis C VLPs Delivered to Dendritic Cells by a TLR2 Targeting Lipopeptide Results in Enhanced Antibody and Cell-Mediated Responses

Although many studies provide strong evidence supporting the development of HCV virus-like particle (VLP)-based vaccines, the fact that heterologous viral vectors and/or multiple dosing regimes are required to induce protective immunity indicates that it is necessary to improve their immunogenicity....

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Main Authors: Chua, Brendon Y., Johnson, Douglas, Tan, Amabel, Earnest-Silveira, Linda, Sekiya, Toshiki, Chin, Ruth, Torresi, Joseph, Jackson, David C.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472981/
https://ncbi.nlm.nih.gov/pubmed/23091628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047492
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