Generation of adaptive immune responses following influenza virus challenge is not compromised by pre-treatment with the TLR-2 agonist Pam2Cys

Immunostimulatory agents provide a new category of anti-microbial agents that activate the host’s innate immune system allowing control of viral and/or bacterial infections. The TLR-2 agonist PEG-Pam2Cys has been shown to mediate potent anti-viral activity against influenza viruses when administered...

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Detalhes bibliográficos
Main Authors: Edin Jessica Mifsud, Amabel Chern-Lyn Tan, Lorena Elizabeth Brown, Brendon Yew Loong Chua, David C. Jackson
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015-06-01
Colecção:Frontiers in Immunology
Assuntos:
Adaptive Immunity
Influenza A virus
innate immunity
Toll-like receptor-2
Pam2Cys
Acesso em linha:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00290/full
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