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Bordetella adenylate cyclase toxin: a unique combination of a pore-forming moiety with a cell-invading adenylate cyclase enzyme

The adenylate cyclase toxin-hemolysin (CyaA, ACT or AC-Hly) is a key virulence factor of the whooping cough agent Bordetella pertussis. CyaA targets myeloid phagocytes expressing the complement receptor 3 (CR3, known as α(M)β(2) integrin CD11b/CD18 or Mac-1) and translocates by a poorly understood m...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Pathog Dis
Prif Awduron: Masin, Jiri, Osicka, Radim, Bumba, Ladislav, Sebo, Peter
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626595/
https://ncbi.nlm.nih.gov/pubmed/26391732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/femspd/ftv075
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