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Adapalene inhibits the activity of cyclin-dependent kinase 2 in colorectal carcinoma
Cyclin-dependent kinase 2 (CDK2) has been reported to be overexpressed in human colorectal cancer; it is responsible for the G1-to-S-phase transition in the cell cycle and its deregulation is a hallmark of cancer. The present study was the first to use idock, a free and open-source protein-ligand do...
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| Pubblicato in: | Mol Med Rep |
|---|---|
| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
D.A. Spandidos
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4626183/ https://ncbi.nlm.nih.gov/pubmed/26398439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2015.4310 |
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