The Role of Structural Elements of the 5'-Terminal Region of p53 mRNA in Translation under Stress Conditions Assayed by the Antisense Oligonucleotide Approach

The p53 protein is one of the major factors responsible for cell cycle regulation and stress response. In the 5’-terminal region of p53 mRNA, an IRES element has been found which takes part in the translational regulation of p53 expression. Two characteristic hairpin motifs are present in this mRNA...

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Vydáno v:PLoS One
Hlavní autoři: Swiatkowska, Agata, Zydowicz, Paulina, Gorska, Agnieszka, Suchacka, Julia, Dutkiewicz, Mariola, Ciesiołka, Jerzy
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626026/
https://ncbi.nlm.nih.gov/pubmed/26513723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141676
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