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The Role of Structural Elements of the 5'-Terminal Region of p53 mRNA in Translation under Stress Conditions Assayed by the Antisense Oligonucleotide Approach

The p53 protein is one of the major factors responsible for cell cycle regulation and stress response. In the 5’-terminal region of p53 mRNA, an IRES element has been found which takes part in the translational regulation of p53 expression. Two characteristic hairpin motifs are present in this mRNA...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Swiatkowska, Agata, Zydowicz, Paulina, Gorska, Agnieszka, Suchacka, Julia, Dutkiewicz, Mariola, Ciesiołka, Jerzy
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626026/
https://ncbi.nlm.nih.gov/pubmed/26513723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141676
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