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Robust and efficient parameter estimation in dynamic models of biological systems

BACKGROUND: Dynamic modelling provides a systematic framework to understand function in biological systems. Parameter estimation in nonlinear dynamic models remains a very challenging inverse problem due to its nonconvexity and ill-conditioning. Associated issues like overfitting and local solutions...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:BMC Syst Biol
Päätekijät: Gábor, Attila, Banga, Julio R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625902/
https://ncbi.nlm.nih.gov/pubmed/26515482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-015-0219-2
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