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Parameter estimation in models of biological oscillators: an automated regularised estimation approach

BACKGROUND: Dynamic modelling is a core element in the systems biology approach to understanding complex biosystems. Here, we consider the problem of parameter estimation in models of biological oscillators described by deterministic nonlinear differential equations. These problems can be extremely...

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Pubblicato in:BMC Bioinformatics
Autori principali: Pitt, Jake Alan, Banga, Julio R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377730/
https://ncbi.nlm.nih.gov/pubmed/30770736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-2630-y
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