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Robust and efficient parameter estimation in dynamic models of biological systems
BACKGROUND: Dynamic modelling provides a systematic framework to understand function in biological systems. Parameter estimation in nonlinear dynamic models remains a very challenging inverse problem due to its nonconvexity and ill-conditioning. Associated issues like overfitting and local solutions...
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| Publicado no: | BMC Syst Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4625902/ https://ncbi.nlm.nih.gov/pubmed/26515482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-015-0219-2 |
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