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Class switching and Myc translocation: how does DNA break?
Chromosomal translocations involving immunoglobulin switch regions are commonly thought to arise from aberrant AID-induced DNA lesions. New data, however, suggest AID does not initiate such lesions, but acts subsequently in the B cell transformation process.
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| Publicado no: | Nat Immunol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4625794/ https://ncbi.nlm.nih.gov/pubmed/15496946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni1104-1101 |
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