Distinct Subpopulations of Nucleus Accumbens Dynorphin Neurons Drive Aversion and Reward

The nucleus accumbens (NAc) and the dynorphinergic system are widely implicated in motivated behaviors. Prior studies have shown that activation of the dynorphin-kappa opioid receptor (KOR) system leads to aversive, dysphoria-like behavior. However, the endogenous sources of dynorphin in these circu...

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Bibliografiset tiedot
Julkaisussa:Neuron
Päätekijät: Al-Hasani, Ream, McCall, Jordan G., Shin, Gunchul, Gomez, Adrian M., Schmitz, Gavin P., Bernardi, Julio M., Pyo, Chang-O., Park, Sung Il, Marcinkiewcz, Catherine M., Crowley, Nicole A., Krashes, Michael J., Lowell, Bradford B., Kash, Thomas L., Rogers, John A., Bruchas, Michael R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625385/
https://ncbi.nlm.nih.gov/pubmed/26335648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2015.08.019
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