Distinct Subpopulations of Nucleus Accumbens Dynorphin Neurons Drive Aversion and Reward

The nucleus accumbens (NAc) and the dynorphinergic system are widely implicated in motivated behaviors. Prior studies have shown that activation of the dynorphin-kappa opioid receptor (KOR) system leads to aversive, dysphoria-like behavior. However, the endogenous sources of dynorphin in these circu...

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Bibliographic Details
Published in:Neuron
Main Authors: Al-Hasani, Ream, McCall, Jordan G., Shin, Gunchul, Gomez, Adrian M., Schmitz, Gavin P., Bernardi, Julio M., Pyo, Chang-O., Park, Sung Il, Marcinkiewcz, Catherine M., Crowley, Nicole A., Krashes, Michael J., Lowell, Bradford B., Kash, Thomas L., Rogers, John A., Bruchas, Michael R.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625385/
https://ncbi.nlm.nih.gov/pubmed/26335648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2015.08.019
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