Locus Coeruleus Kappa-Opioid Receptors Modulate Reinstatement of Cocaine Place Preference Through a Noradrenergic Mechanism

Activation of kappa-opioid receptors (KORs) in monoamine circuits results in dysphoria-like behaviors and stress-induced reinstatement of drug seeking in both conditioned place preference (CPP) and self-administration models. Noradrenergic (NA) receptor systems have also been implicated in similar b...

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Detalhes bibliográficos
Main Authors: Al-Hasani, Ream, McCall, Jordan G, Foshage, Audra M, Bruchas, Michael R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799068/
https://ncbi.nlm.nih.gov/pubmed/23787819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.151
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