Dynorphin controls the gain of an amygdalar anxiety circuit

Kappa opioid receptors (KORs) are involved in a variety of aversive behavioral states, including anxiety. To date, a circuit based mechanism for KOR driven anxiety has not been described. Here we show that activation of KORs inhibits glutamate release from the basolateral amygdala (BLA) inputs to th...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Crowley, Nicole A., Bloodgood, Daniel W., Hardaway, J. Andrew, Kendra, Alexis, McCall, Jordan G., Al-Hasani, Ream, McCall, Nora M., Yu, Waylin, Schools, Zachary L., Krashes, Michael J., Lowell, Bradford B., Whistler, Jennifer L., Bruchas, Michael R., Kash, Thomas L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814306/
https://ncbi.nlm.nih.gov/pubmed/26997280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.02.069
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