Nicotine aversion is mediated by GABAergic interpeduncular nucleus inputs to laterodorsal tegmentum

Nicotine use can lead to dependence through complex processes that are regulated by both its rewarding and aversive effects. Recent studies show that aversive nicotine doses activate excitatory inputs to the interpeduncular nucleus (IPN) from the medial habenula (MHb), but the downstream targets of...

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Pubblicato in:Nat Commun
Autori principali: Wolfman, Shannon L., Gill, Daniel F., Bogdanic, Fili, Long, Katie, Al-Hasani, Ream, McCall, Jordan G., Bruchas, Michael R., McGehee, Daniel S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6045623/
https://ncbi.nlm.nih.gov/pubmed/30006624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04654-2
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