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Nicotine aversion is mediated by GABAergic interpeduncular nucleus inputs to laterodorsal tegmentum

Nicotine use can lead to dependence through complex processes that are regulated by both its rewarding and aversive effects. Recent studies show that aversive nicotine doses activate excitatory inputs to the interpeduncular nucleus (IPN) from the medial habenula (MHb), but the downstream targets of...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Wolfman, Shannon L., Gill, Daniel F., Bogdanic, Fili, Long, Katie, Al-Hasani, Ream, McCall, Jordan G., Bruchas, Michael R., McGehee, Daniel S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6045623/
https://ncbi.nlm.nih.gov/pubmed/30006624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04654-2
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