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Broad CTL Response in Early HIV Infection Drives Multiple Concurrent CTL Escapes

Recent studies have highlighted the ability of HIV to escape from cytotoxic T lymphocyte (CTL) responses that concurrently target multiple viral epitopes. Yet, the viral dynamics involved in such escape are incompletely understood. Previous analyses have made several strong assumptions regarding HIV...

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Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Leviyang, Sivan, Ganusov, Vitaly V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624722/
https://ncbi.nlm.nih.gov/pubmed/26506433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004492
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