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Predicting the Effect of Mutations on Protein-Protein Binding Interactions through Structure-Based Interface Profiles
The formation of protein-protein complexes is essential for proteins to perform their physiological functions in the cell. Mutations that prevent the proper formation of the correct complexes can have serious consequences for the associated cellular processes. Since experimental determination of pro...
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Publicado no: | PLoS Comput Biol |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4624718/ https://ncbi.nlm.nih.gov/pubmed/26506533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004494 |
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