E2-EPF UCP regulates stability and functions of missense mutant pVHL via ubiquitin mediated proteolysis

BACKGROUND: Missense mutation of VHL gene is frequently detected in type 2 VHL diseases and linked to a wide range of pVHL functions and stability. Certain mutant pVHLs retain ability to regulate HIFs but lose their function by instability. In this case, regulating of degradation of mutant pVHLs, ca...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Park, Kyeong-Su, Kim, Ju Hee, Shin, Hee Won, Chung, Kyung-Sook, Im, Dong-Soo, Lim, Jung Hwa, Jung, Cho-Rok
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624580/
https://ncbi.nlm.nih.gov/pubmed/26503325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1786-8
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados