Adenovirus-mediated E2-EPF UCP Gene Transfer Prevents Autoamputation in a Mouse Model of Hindlimb Ischemia

E2-EPF ubiquitin carrier protein (UCP) stabilizes hypoxia-inducible factor-1α (HIF-1α) inducing ischemic vascular responses. Here, we investigated the effect of UCP gene transfer on therapeutic angiogenesis. Adenovirus-encoded UCP (Ad-F-UCP) increased the expression of vascular endothelial growth fa...

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Autori principali: Lim, Jung Hwa, Shin, Hyo Jung, Park, Kyeong-Su, Lee, Chan Hee, Jung, Cho-Rok, Im, Dong-Soo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321605/
https://ncbi.nlm.nih.gov/pubmed/22294149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.302
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