E2-EPF UCP Possesses E3 Ubiquitin Ligase Activity via Its Cysteine 118 Residue

Here, we show that E2-EPF ubiquitin carrier protein (UCP) elongated E3-independent polyubiquitin chains on the lysine residues of von Hippel-Lindau protein (pVHL) and its own lysine residues both in vitro and in vivo. The initiation of the ubiquitin reaction depended on not only Lys11 linkage but al...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lim, Jung Hwa, Shin, Hee Won, Chung, Kyung-Sook, Kim, Nam-Soon, Kim, Ju Hee, Jung, Hong-Ryul, Im, Dong-Soo, Jung, Cho-Rok
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042379/
https://ncbi.nlm.nih.gov/pubmed/27685940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163710
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados