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Limited Effect of Chronic Valproic Acid Treatment in a Mouse Model of Machado-Joseph Disease
Machado-Joseph disease (MJD) is an inherited neurodegenerative disease, caused by a CAG repeat expansion within the coding region of ATXN3 gene, and which currently lacks effective treatment. In this work we tested the therapeutic efficacy of chronic treatment with valproic acid (VPA) (200mg/kg), a...
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| Publicado no: | PLoS One |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4624233/ https://ncbi.nlm.nih.gov/pubmed/26505994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141610 |
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