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Citalopram reduces aggregation of ATXN3 in a YAC transgenic mouse model of Machado-Joseph disease
Machado-Joseph disease, also known as Spinocerebellar ataxia type 3, is a fatal polyglutamine disease with no disease-modifying treatment. The selective serotonin reuptake inhibitor citalopram was shown in nematode and mouse models to be a compelling repurposing candidate for Machado-Joseph disease...
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| 出版年: | Mol Neurobiol |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6417975/ https://ncbi.nlm.nih.gov/pubmed/30187384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-018-1331-2 |
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