Effect of treadmill exercise on PI3K/AKT/mTOR, autophagy, and Tau hyperphosphorylation in the cerebral cortex of NSE/htau23 transgenic mice

PURPOSE: Neurofibrillary tangles, one of pathological features of Alzheimer’s disease, are produced by the hyperphosphorylation and aggregation of tau protein. This study aimed to investigate the effects of treadmill exercise on PI3K/AKT/mTOR signal transmission, autophagy, and cognitive ability tha...

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Bibliographic Details
Published in:J Exerc Nutrition Biochem
Main Authors: Kang, Eun-Bum, Cho, Joon-Yong
Format: Artigo
Language:Inglês
Published: Korean Society for Exercise Nutrition 2015
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624121/
https://ncbi.nlm.nih.gov/pubmed/26527331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5717/jenb.2015.15090806
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