Antigenic sites on the H(N) domain of botulinum neurotoxin A stimulate protective antibody responses against active toxin

Botulinum neurotoxins (BoNTs) are the most toxic substances known. BoNT intoxicates cells in a highly programmed fashion initiated by binding to the cell surface, internalization and enzymatic cleavage of substrate, thus, inhibiting synaptic exocytosis. Over the past two decades, immunological signi...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Vijayalakshmi Ayyar, B., Tajhya, Rajeev B., Beeton, Christine, Zouhair Atassi, M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623786/
https://ncbi.nlm.nih.gov/pubmed/26508475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15776
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky