Distinct DNA damage determines differential phosphorylation of Chk2

Checkpoint kinase 2 (Chk2) has been implicated in DNA damage signaling. By using BJ human fibroblasts, HCT116 colorectal cancer cells and HeLa cervical cancer cells, we further detailed phosphorylation kinetics of Chk2 under treatment with neocarcinostatin (NCS) or doxorubicin (Dox). After NCS treat...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Cancer Biol Ther
Päätekijät: Ouchi, Mutsuko, Ouchi, Toru
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2014
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623534/
https://ncbi.nlm.nih.gov/pubmed/25535901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384047.2014.972823
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