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Distinct DNA damage determines differential phosphorylation of Chk2
Checkpoint kinase 2 (Chk2) has been implicated in DNA damage signaling. By using BJ human fibroblasts, HCT116 colorectal cancer cells and HeLa cervical cancer cells, we further detailed phosphorylation kinetics of Chk2 under treatment with neocarcinostatin (NCS) or doxorubicin (Dox). After NCS treat...
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| Publicado no: | Cancer Biol Ther |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4623534/ https://ncbi.nlm.nih.gov/pubmed/25535901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384047.2014.972823 |
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