Surrogate target cells expressing surface anti-idiotype antibody for the clinical evaluation of an internalizing CD22-specific antibody

SM03, a chimeric antibody that targets the B-cell restricted antigen CD22, is currently being clinically evaluated for the treatment of lymphomas and other autoimmune diseases in China. SM03 binding to surface CD22 leads to rapid internalization, making the development of an appropriate cell-based b...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Leung, Shui-on, Gao, Kai, Wang, Guang Yu, Cheung, Benny Ka-wa, Lee, Kwan-yeung, Zhao, Qi, Cheung, Wing-Tai, Wang, Jun Zhi
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623522/
https://ncbi.nlm.nih.gov/pubmed/25427174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19420862.2014.985519
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