Surrogate target cells expressing surface anti-idiotype antibody for the clinical evaluation of an internalizing CD22-specific antibody

SM03, a chimeric antibody that targets the B-cell restricted antigen CD22, is currently being clinically evaluated for the treatment of lymphomas and other autoimmune diseases in China. SM03 binding to surface CD22 leads to rapid internalization, making the development of an appropriate cell-based b...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:MAbs
Prif Awduron: Leung, Shui-on, Gao, Kai, Wang, Guang Yu, Cheung, Benny Ka-wa, Lee, Kwan-yeung, Zhao, Qi, Cheung, Wing-Tai, Wang, Jun Zhi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2014
Pynciau:
Reports
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623522/
https://ncbi.nlm.nih.gov/pubmed/25427174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19420862.2014.985519
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