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Generation of Anti-Idiotype scFv for Pharmacokinetic Measurement in Lymphoma Patients Treated with Chimera Anti-CD22 Antibody SM03

Pre-clinical and clinical studies of therapeutic antibodies require highly specific reagents to examine their immune responses, bio-distributions, immunogenicity, and pharmacodynamics in patients. Selective antigen-mimicking anti-idiotype antibody facilitates the assessment of therapeutic antibody i...

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Sonraí Bibleagrafaíochta
Main Authors: Zhao, Qi, Wong, Pui-Fan, Lee, Susanna S. T., Leung, Shui-On, Cheung, Wing-Tai, Wang, Jun-Zhi
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015983/
https://ncbi.nlm.nih.gov/pubmed/24816427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096697
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