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Expression Optimization of Anti-CD22 scFv-Apoptin Fusion Protein Using Experimental Design Methodology

BACKGROUND: Design of experiments is a rapid and cost-effective approach for optimization of recombinant protein production process. In our previous study, we generated a potent dual-acting fusion protein, anti-CD22 scFv-apoptin, to target B-cell malignant cell lines. In the present investigation, w...

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Vydáno v:Iran Biomed J
Hlavní autoři: Amiri, Solmaz Agha, Zarei, Najmeh, Enayati, Somayeh, Azizi, Mohammad, Khalaj, Vahid, Shahhosseini, Soraya
Médium: Artigo
Jazyk:Inglês
Vydáno: Pasteur Institute 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5712387/
https://ncbi.nlm.nih.gov/pubmed/28689385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22034/ibj.22.1.66
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