A novel anti-CD22 scFv–apoptin fusion protein induces apoptosis in malignant B-cells

CD22 marker is a highly internalizing antigen which is located on the surface of B-cells and is being used as a promising target for treatment of B cell malignancies. Monoclonal antibodies targeting CD22 have been introduced and some are currently under investigation in clinical trials. Building on...

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Publicat a:AMB Express
Autors principals: Agha Amiri, Solmaz, Shahhosseini, Soraya, Zarei, Najmeh, Khorasanizadeh, Dorsa, Aminollahi, Elahe, Rezaie, Faegheh, Zargari, Mehryar, Azizi, Mohammad, Khalaj, Vahid
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2017
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457376/
https://ncbi.nlm.nih.gov/pubmed/28582973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13568-017-0410-5
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