Regulation of dimethyl-fumarate toxicity by proteasome inhibitors

The present studies examined the biology of the multiple sclerosis drug dimethyl-fumarate (DMF) or its in vivo breakdown product and active metabolite mono-methyl-fumarate (MMF), alone or in combination with proteasome inhibitors, in primary human glioblastoma (GBM) cells. MMF enhanced velcade and c...

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Bibliografiske detaljer
Udgivet i:Cancer Biol Ther
Main Authors: Booth, Laurence, Cruickshanks, Nichola, Tavallai, Seyedmehrad, Roberts, Jane L, Peery, Matthew, Poklepovic, Andrew, Dent, Paul
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2014
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623310/
https://ncbi.nlm.nih.gov/pubmed/25482938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384047.2014.967992
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