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PDE5 Inhibitors Enhance Celecoxib Killing in Multiple Tumor Types

The present studies determined whether clinically relevant phosphodiesterase 5 (PDE5) inhibitors interacted with a clinically relevant NSAID, celecoxib, to kill tumor cells. Celecoxib and PDE5 inhibitors interacted in a greater than additive fashion to kill multiple tumor cell types. Celecoxib and s...

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Detalhes bibliográficos
Publicado no:J Cell Physiol
Main Authors: BOOTH, LAURENCE, ROBERTS, JANE L., CRUICKSHANKS, NICHOLA, TAVALLAI, SEYEDMEHRAD, WEBB, TIMOTHY, SAMUEL, PETER, CONLEY, ADAM, BINION, BRITTANY, YOUNG, HAROLD F., POKLEPOVIC, ANDREW, SPIEGEL, SARAH, DENT, PAUL
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398314/
https://ncbi.nlm.nih.gov/pubmed/25303541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24843
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