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Gli2 silencing enhances TRAIL-induced apoptosis and reduces tumor growth in human hepatoma cells in vivo

Our previous studies have showed that Gli2 played a predominant role in proliferation and apoptosis resistance to TRAIL in hepatoma cells. The purpose of this study was to explore whether Gli2 silencing enhances efficiency of TRAIL for hepatoma in vivo. SMMC-7721-shRNA cells were implanted subcutane...

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Publicat a:Cancer Biol Ther
Autors principals: Zhang, Da-wei, Li, Hai-yan, Lau, Wan-yee, Cao, Liang-qi, Li, Yue, Jiang, Xiao-feng, Yang, Xue-wei, Xue, Ping
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622984/
https://ncbi.nlm.nih.gov/pubmed/25535898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384047.2014.972286
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