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Silencing of mutant p53 by siRNA induces cell cycle arrest and apoptosis in human bladder cancer cells
BACKGROUND: p53 is the most frequently mutated tumor-suppressor gene in human cancers. It has been reported that mutations in p53 result not only in the loss of its ability as a tumor suppressor, but also in the gain of novel cancer-related functions that contribute to oncogenesis. The present study...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3565885/ https://ncbi.nlm.nih.gov/pubmed/23356234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7819-11-22 |
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