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Gli2 silencing enhances TRAIL-induced apoptosis and reduces tumor growth in human hepatoma cells in vivo

Our previous studies have showed that Gli2 played a predominant role in proliferation and apoptosis resistance to TRAIL in hepatoma cells. The purpose of this study was to explore whether Gli2 silencing enhances efficiency of TRAIL for hepatoma in vivo. SMMC-7721-shRNA cells were implanted subcutane...

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Библиографические подробности
Опубликовано в: :Cancer Biol Ther
Главные авторы: Zhang, Da-wei, Li, Hai-yan, Lau, Wan-yee, Cao, Liang-qi, Li, Yue, Jiang, Xiao-feng, Yang, Xue-wei, Xue, Ping
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622984/
https://ncbi.nlm.nih.gov/pubmed/25535898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384047.2014.972286
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